Principal Cheminformatician
- southampton, hampshire, SO14 0QQ, United Kingdom
- Permanent·Remote
- Full time
- £98,000 - £98,000 Per Annum
Job Description
About the Role
Our client is seeking a highly skilled Principal Cheminformatician to join their world-class computational chemistry team, operating in a fully remote capacity. This senior role is crucial for driving innovation in drug discovery by developing and implementing advanced cheminformatics tools and strategies. You will be responsible for managing large chemical datasets, developing predictive models, and supporting medicinal chemistry programs with data-driven insights. This is an exceptional opportunity for an experienced cheminformatician to contribute significantly to cutting-edge research and influence the direction of drug design from anywhere, fostering a collaborative and high-impact remote working culture.
Key Responsibilities
- Develop and maintain large-scale chemical databases and knowledge management systems.
- Design, implement, and validate predictive computational models for ADMET properties, biological activity, and selectivity.
- Apply machine learning and data mining techniques to extract insights from chemical and biological data.
- Collaborate closely with medicinal chemists, computational chemists, and biologists to support drug design campaigns.
- Mentor junior cheminformaticians and contribute to the strategic planning of computational chemistry initiatives.
Requirements
- PhD or Master's degree in Cheminformatics, Computational Chemistry, Computer Science, or a related quantitative field.
- Minimum of 6 years of experience in cheminformatics within the pharmaceutical or biotechnology industry.
- Proficiency in programming languages such as Python and experience with cheminformatics toolkits (e.g., RDKit, KNIME).
- Strong understanding of QSAR, molecular modeling, and statistical analysis methods.
- Excellent problem-solving abilities and strong communication skills for remote collaboration.
Benefits
- A highly competitive salary and performance-based bonus.
- Fully remote work arrangement with flexible hours.
- Comprehensive health, dental, and vision insurance.
- Generous contribution to a pension plan.
- Opportunities for professional growth and engagement in groundbreaking research.


