Senior Process Development Scientist

About the Role

Our client is seeking a highly experienced Senior Process Development Scientist to lead process optimization and scale-up activities for novel biopharmaceutical products in Bristol . This role is critical for translating laboratory-scale discoveries into robust, scalable manufacturing processes that meet stringent quality and regulatory standards. You will work with cutting-edge bioprocessing technologies and collaborate closely with manufacturing and quality assurance teams. This is an ideal opportunity for a seasoned scientist to drive process innovation and contribute to the reliable supply of essential medicines.

Key Responsibilities

• Design, execute, and analyze experiments to optimize upstream and downstream bioprocessing steps, including cell culture, fermentation, purification, and formulation.
• Develop scalable and robust manufacturing processes that meet defined quality attributes and regulatory requirements.
• Lead technology transfer activities from R&D to pilot plant and manufacturing sites, providing technical support.
• Troubleshoot process deviations and implement corrective and preventative actions (CAPAs).
• Characterize process parameters and product attributes, ensuring process understanding and control.
• Author technical reports, process descriptions, and contribute to regulatory filings.

Requirements

• PhD in Biochemical Engineering, Chemical Engineering, Biotechnology, or a related discipline.
• Minimum of 7 years of experience in process development for biopharmaceuticals (e.g., mAbs, recombinant proteins, vaccines).
• In-depth knowledge of microbial fermentation or mammalian cell culture processes.
• Strong experience with downstream purification techniques (e.g., chromatography, filtration).
• Familiarity with process analytical technology (PAT) and statistical process control (SPC).
• Excellent project management, communication, and interpersonal skills for effective teamwork and leadership in Bristol .

Benefits

• Competitive salary and comprehensive benefits package.
• Significant opportunities for career advancement and professional growth.
• Access to state-of-the-art bioprocessing facilities and pilot plants.
• Collaborative working environment focused on innovation and quality.
• Relocation assistance may be available for highly qualified candidates.