Senior Research Chemist - Organic Synthesis

About the Role

Our client is seeking a highly skilled Senior Research Chemist with expertise in Organic Synthesis to join their innovative R&D team in Plymouth . This role is central to the design and execution of complex synthetic routes for novel compounds, driving forward early-stage drug discovery programs. You will be responsible for tackling challenging synthetic problems, optimizing reaction conditions, and developing scalable processes for potential new therapeutics. Working in a hybrid capacity, you will contribute both in the laboratory and through remote analysis and reporting, collaborating closely with medicinal chemists and biologists to achieve project goals.

Key Responsibilities

• Design and synthesize novel organic molecules using a wide range of synthetic methodologies.
• Develop and optimize synthetic routes, focusing on efficiency, scalability, and safety.
• Characterize synthesized compounds using spectroscopic techniques (NMR, MS, IR) and chromatographic methods (HPLC, GC).
• Troubleshoot synthetic challenges and implement creative solutions to overcome obstacles.
• Collaborate with medicinal chemists to advance lead optimization programs.
• Maintain detailed experimental records and contribute to scientific reports and publications.

Requirements

• PhD in Organic Chemistry or a closely related field.
• Minimum of 5 years of post-doctoral or industry experience in synthetic organic chemistry.
• Demonstrated expertise in multi-step organic synthesis and reaction mechanism understanding.
• Proficiency with modern spectroscopic and analytical techniques for compound characterization.
• Experience with purification techniques such as chromatography.
• Strong problem-solving abilities and excellent organizational skills for laboratory work and remote analysis.

Benefits

• Competitive salary and benefits package, including performance incentives.
• Hybrid working model offering flexibility between the Plymouth lab and remote work.
• Opportunity to work on cutting-edge research in a stimulating scientific environment.
• Access to advanced synthetic and analytical equipment.
• Support for professional development, including attendance at chemistry conferences.
• A collaborative and innovative research culture.