Senior Scientist - Structural Biology

About the Role

Our client is seeking a highly skilled and motivated Senior Scientist specializing in Structural Biology to join their dynamic research team in Norwich . This role is integral to understanding the molecular mechanisms of disease and designing novel therapeutic agents. You will employ advanced structural biology techniques to elucidate protein structures, characterize drug-target interactions, and contribute significantly to the drug discovery pipeline. Working within a state-of-the-art facility, you will collaborate with a multidisciplinary team, driving scientific innovation and advancing critical research objectives.

Key Responsibilities

• Determine protein structures using techniques such as X-ray crystallography and/or cryo-electron microscopy (cryo-EM).
• Characterize protein-ligand interactions and their impact on biological function.
• Develop and optimize experimental protocols for protein expression, purification, and crystallization.
• Analyze and interpret complex structural data, including electron density maps and molecular models.
• Collaborate with computational chemists and medicinal chemists to guide structure-based drug design efforts.
• Present research findings to internal teams and at scientific conferences.

Requirements

• PhD in Structural Biology, Biochemistry, Biophysics, or a related field.
• Minimum of 5 years of relevant post-doctoral or industry experience in structural biology.
• Proven expertise in X-ray crystallography and/or cryo-EM, including data collection and structure determination.
• Experience with protein expression, purification, and biochemical characterization is essential.
• Strong analytical, problem-solving, and communication skills.

Benefits

• Competitive salary and comprehensive benefits package, including health, dental, and vision insurance.
• Performance-based bonus and opportunities for career advancement.
• Generous paid time off and a supportive work-life balance.
• Access to cutting-edge structural biology equipment and facilities.
• Support for professional development, including conference attendance and continued learning.