Senior Scientist - Toxicology

Role Overview

We are currently looking for a Senior Scientist, Toxicology to join our client’s biosciences team based in the Edinburgh area. As the Senior Scientist, Toxicology you will be responsible for designing and delivering human-relevant studies that support pharmaceutical, chemical and consumer product safety assessment programmes.

This senior laboratory-based position combines independent scientific delivery with opportunities to act as Study Director, lead client-facing activities and develop less-experienced colleagues. Reporting to the Team Leader, Toxicology & Bioanalysis, you will work across toxicology, bioanalysis and biosciences on regulated and non-regulated studies.

As Senior Scientist, Toxicology, you will help advance New Approach Methodologies, mechanistic toxicology and endocrine disruption assessment, translating complex experimental findings into reliable evidence for safety decisions.

Key Duties And Responsibilities

Your duties as the Senior Scientist, Toxicology will be varied however the key duties and responsibilities are as follows:

1. Independently design, conduct, analyse and interpret toxicology studies using cell-based, biochemical and human-relevant assay systems. You will apply New Approach Methodologies, primary cells and established cell lines to investigate endpoints including hormone and thyroid disruption, cytochrome P450 inhibition and cytotoxicity, using radioactive and non-radioactive approaches.

1. Act as Study Director or scientific lead for Good Laboratory Practice and research and development studies. You will manage scientific projects and competing priorities, resolve technical challenges and maintain scientific, regulatory and safety standards, ensuring compliance with applicable organisational and legal requirements.

1. Lead scientific discussions with clients, build productive relationships and deliver clear reports, presentations and other scientific outputs. You will contribute to proposals, scientific business development, publications, conference presentations and appropriate marketing activities, working with multidisciplinary colleagues to support project goals, innovation, operational effectiveness and service development.

1. Train, supervise and support less-experienced scientists in laboratory techniques, equipment use and data interpretation. You will strengthen data governance, quality and reproducibility through accurate documentation, compliant archiving and time recording, while contributing to standard operating procedures, audit responses, corrective and preventive actions and continuous improvement.

Role Requirements

To be successful in your application to this exciting opportunity as the Senior Scientist, Toxicology we are looking to identify the following on your profile and past history:

1. A relevant doctorate in Analytical Chemistry, Bioanalysis, Pharmaceutical Sciences or a related discipline, or equivalent industry experience. You will bring proven drug discovery experience gained within a pharmaceutical, biotechnology or contract research environment, alongside strong scientific judgement, problem-solving and decision-making skills.

1. Proven industry experience in preclinical toxicology, including work under Good Laboratory Practice and the ability to train others, plus Study Director experience across regulated and research and development studies. Your background will include New Approach Methodologies, primary cells, established cell lines, and radioactive and non-radioactive cell-based and biochemical assays addressing hormone and thyroid disruption, cytochrome P450 inhibition and cytotoxicity.

1. A working knowledge and practical experience with scientific project leadership, customer management and communicating complex data, underpinned by accountability, collaboration and a commitment to data integrity and reproducibility. Desirable experience includes regulated and non-regulated bioanalysis, Test Facility Manager responsibilities, holding a Controlled Drugs Licence, Responsible Party duties for radioactive materials or substances, and supporting proposals, scientific business development and wider team objectives.

Key Words:

Preclinical Toxicology / Senior Scientist / Study Director / New Approach Methodologies / Cell-Based Assays / Endocrine Disruption / Good Laboratory Practice / Bioanalysis / Safety Assessment / Mechanistic Toxicology

Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer. We welcome applications from anyone who meets the role requirements. HRS exclusively supports the Life Science sectors, combining recruitment expertise with scientific knowledge to help you advance your career