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Senior Scientist - Medicinal Chemistry
- bristol, south west england, BS1 4AG, United Kingdom
- Full time
- £78,000 - £78,000 Per Annum
Job Description
About the Role
Our client is seeking a highly skilled Senior Scientist in Medicinal Chemistry to join their innovative drug discovery team based in Bristol . This role is central to designing and synthesizing novel small molecules with therapeutic potential, driving forward the early stages of drug development. You will work in a state-of-the-art chemistry laboratory, collaborating closely with biologists and computational chemists to optimize compound properties and advance promising drug candidates. This is an exciting opportunity for an experienced medicinal chemist to contribute to impactful research and shape the future of pharmaceutical innovation.
Key Responsibilities
- Design and synthesize novel small molecules for targeted therapeutic areas, applying principles of medicinal chemistry.
- Optimize lead compounds through iterative cycles of design, synthesis, and in vitro testing.
- Collaborate closely with biologists and computational chemists to define structure-activity relationships (SAR).
- Develop and implement efficient synthetic routes and purification strategies.
- Characterize synthesized compounds using analytical techniques such as NMR, LC-MS, and HPLC.
- Maintain detailed experimental records and contribute to scientific reports and publications.
Requirements
- PhD in Medicinal Chemistry or Organic Chemistry with a strong focus on drug discovery.
- A minimum of 5 years of post-doctoral experience in medicinal chemistry within the pharmaceutical or biotechnology industry.
- Proven track record of successfully contributing to drug discovery projects, demonstrated by a strong publication record or patent portfolio.
- Extensive experience with modern synthetic organic chemistry techniques and instrumentation.
- Familiarity with structure-based drug design and computational chemistry tools.
- Excellent problem-solving abilities and strong communication skills.
Benefits
- Competitive salary and attractive bonus scheme.
- Comprehensive health, dental, and vision insurance.
- Generous pension scheme and life assurance.
- Opportunities for professional development and attending scientific conferences.
- Access to cutting-edge synthetic and analytical equipment in Bristol .
- A highly collaborative and innovative research environment.